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Integrative Psychiatry & Longevity Blog in St. Louis, MO & Washington DC
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Fish Oil Didn’t Prevent Alzheimer’s. Here’s Why That Doesn’t Mean Fish Oil Doesn’t Work.
TL;DR: A recent study from Keck Medicine of USC found that omega-3 fish oil supplements did not significantly slow Alzheimer’s-related cognitive decline. That finding isn’t particularly surprising—and it doesn’t mean fish oil is ineffective. Alzheimer’s disease is increasingly understood as a disorder of impaired brain energy metabolism, insulin resistance, mitochondrial dysfunction, inflammation, and vascular disease. Fish oil supports healthy brain cell membranes, neurotran
Ryan Sheridan, NP


Could ADHD Be a Metabolic Disorder? What New Ketogenic Diet Research Means for Mental Health
TL;DR Emerging research in metabolic psychiatry is challenging the traditional view that mental health conditions are solely disorders of neurotransmitters. New studies suggest that conditions such as depression, bipolar disorder, schizophrenia, and potentially ADHD may also involve dysfunction in how the brain produces and uses energy. While ketogenic diets are not a cure-all, they have shown promising early results in several psychiatric conditions, highlighting the importa
Ryan Sheridan, NP


ADHD May Be a Brain Energy Disorder: What a Major New Review Means for Children, Adults, and the Future of Treatment
TL;DR: ADHD May Be a Brain Energy Disorder A major 2026 review published in Neuroscience & Biobehavioral Reviews proposes a new way of thinking about ADHD. Rather than viewing ADHD solely as a disorder of attention, the authors suggest ADHD may involve difficulties regulating and allocating the brain’s energy resources. While this model is still evolving, it helps explain why people with ADHD often experience inconsistent performance, fluctuating focus, executive dysfunction,
Ryan Sheridan, NP


Could GLP-1 Medications Help Prevent Alzheimer’s Disease? What the New Research Means for Brain Health, ADHD, and Integrative Psychiatry
By Ryan Sheridan, DNP, PMHNP-BC | Proactive Psychiatry TL;DR A new 2026 systematic review suggests that GLP-1 receptor agonists (GLP-1 medications) may have significant neuroprotective effects that extend far beyond weight loss and diabetes treatment. In animal models, these medications consistently reduced two of Alzheimer’s disease’s hallmark pathologies: amyloid-beta plaques and tau tangles. Human studies remain limited, but early evidence suggests GLP-1 medications may im
Ryan Sheridan, NP


Omega-3s for Mental Health, Mood, and ADHD: What Patients Should Know
Most people have heard omega-3s are “good for your heart.” Fewer people understand why they matter for the brain. That is unfortunate, because the brain is not just a bag of neurotransmitters floating around waiting for a medication to fix everything. The brain is tissue. It is made of cells, membranes, fats, mitochondria, inflammatory signaling molecules, and electrical networks. When we talk about mental health from an integrative psychiatry perspective, we have to talk abo
Ryan Sheridan, NP


Why Alcohol, Cannabis, “Sleep Pills,” and Benzodiazepines Are Messing With Your Sleep (and What Actually Works)
Sleep isn’t just “something we do at night.” It’s a biologically essential process that repairs the brain, consolidates memory, balances mood, regulates appetite, and clears the brain’s metabolic waste. When sleep goes sideways, everything else goes sideways: mood, focus, resilience, and yes, health. It's fairly common to rely on substances to “hack” sleep, and while these may feel helpful in the short term, they throw your brain’s natural sleep architecture out of whack. L
Ryan Sheridan, NP


The Metabolic Psychiatry Revolution: Why Exercise Should Be the First Treatment for Mental Health
A New Wave of Mental Health Research: Exercise as a First-Line Treatment For decades, mental health treatment has followed a predictable...
Ryan Sheridan, NP


Why is ADHD So Common? ADHD Isn’t the Problem—The System Is
ADHD isn’t a disorder. Not really - so screw what the DSM says. It’s a mismatch between how your brain works and what society expects...
Ryan Sheridan, NP


ADHD: A Crisis of Diagnosis, Outcomes, and the Need for Real Solutions
Attention-Deficit/Hyperactivity Disorder (ADHD) has become one of the most talked-about mental health conditions in the last few decades,...
Ryan Sheridan, NP


Why My Washington, D.C.-Based Integrative Psychiatry Practice is Better for ADHD than ADHD Online, Done, and Other Telehealth Platforms
TL;DR: Key Takeaways • My practice, Proactive Psychiatry, offers a personalized, holistic approach. • I spend more time with each...
Ryan Sheridan, NP


Understanding the Role of Dopamine in ADHD: A Guide to Lasting Change
Attention-Deficit/Hyperactivity Disorder (ADHD) is a complex condition often linked to dopamine dysregulation. (Yeah, for those who have...
Ryan Sheridan, NP


The Ultimate Guide to Mastering High-Quality Sleep: Insights from an Integrative Psychiatric Nurse Practitioner
High-quality sleep has the power to transform your life. I will try to keep this post brief. (Also, not exactly sure why I chose all cats...
Ryan Sheridan, NP


Mastering Adult ADHD: Embracing Your Unique Strengths and Building a Balanced Life
ADHD in adulthood often feels like trying to fit a square peg into a round hole. Society expects us to stay still, focus, and follow...
Ryan Sheridan, NP


ADHD: Rethinking the “Disorder” as a Cognitive Difference
As an integrative psychiatric nurse practitioner in Washington, DC , I often encounter folks diagnosed with ADHD who feel limited by the...
Ryan Sheridan, NP


ADHD Across Ages: Integrative Approaches in Washington, D.C.
As an integrative psychiatric nurse practitioner based in Washington, D.C., I am uniquely positioned to observe the challenges and...
Ryan Sheridan, NP
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