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Integrative Psychiatry & Longevity Blog in St. Louis, MO & Washington DC
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Fish Oil Didn’t Prevent Alzheimer’s. Here’s Why That Doesn’t Mean Fish Oil Doesn’t Work.
TL;DR: A recent study from Keck Medicine of USC found that omega-3 fish oil supplements did not significantly slow Alzheimer’s-related cognitive decline. That finding isn’t particularly surprising—and it doesn’t mean fish oil is ineffective. Alzheimer’s disease is increasingly understood as a disorder of impaired brain energy metabolism, insulin resistance, mitochondrial dysfunction, inflammation, and vascular disease. Fish oil supports healthy brain cell membranes, neurotran
Ryan Sheridan, NP


ADHD May Be a Brain Energy Disorder: What a Major New Review Means for Children, Adults, and the Future of Treatment
TL;DR: ADHD May Be a Brain Energy Disorder A major 2026 review published in Neuroscience & Biobehavioral Reviews proposes a new way of thinking about ADHD. Rather than viewing ADHD solely as a disorder of attention, the authors suggest ADHD may involve difficulties regulating and allocating the brain’s energy resources. While this model is still evolving, it helps explain why people with ADHD often experience inconsistent performance, fluctuating focus, executive dysfunction,
Ryan Sheridan, NP


Omega-3s for Mental Health, Mood, and ADHD: What Patients Should Know
Most people have heard omega-3s are “good for your heart.” Fewer people understand why they matter for the brain. That is unfortunate, because the brain is not just a bag of neurotransmitters floating around waiting for a medication to fix everything. The brain is tissue. It is made of cells, membranes, fats, mitochondria, inflammatory signaling molecules, and electrical networks. When we talk about mental health from an integrative psychiatry perspective, we have to talk abo
Ryan Sheridan, NP


Understanding Brain Energy: The Role of Creatine in Mental Health
There’s a tendency in mental health to jump straight to neurotransmitters, diagnoses, and medications. Sometimes that’s appropriate. But more often than we’d like to admit, we overlook something foundational: how the brain is fueled in the first place. A recent randomized controlled trial published in the Cell Metabolism journal, highlighted and broken down by Nick Norwitz, adds an important layer to that conversation. It suggests that depression, at least in part, may involv
Ryan Sheridan, NP


Why Alcohol, Cannabis, “Sleep Pills,” and Benzodiazepines Are Messing With Your Sleep (and What Actually Works)
Sleep isn’t just “something we do at night.” It’s a biologically essential process that repairs the brain, consolidates memory, balances mood, regulates appetite, and clears the brain’s metabolic waste. When sleep goes sideways, everything else goes sideways: mood, focus, resilience, and yes, health. It's fairly common to rely on substances to “hack” sleep, and while these may feel helpful in the short term, they throw your brain’s natural sleep architecture out of whack. L
Ryan Sheridan, NP


Melatonin Isn’t a Sleep Fix — It’s a Signal: Thoughts from an Integrative Psych NP
Lately, more and more people are turning to melatonin to help them fall asleep. You can find it on every pharmacy shelf, marketed as the natural solution for restless nights. And while melatonin does have a role to play in regulating sleep, the idea that it’s a shortcut or substitute for good sleep habits is where many people go wrong. As an integrative psychiatric nurse practitioner , I work with patients every day who struggle with sleep. And the truth is, good sleep doesn
Ryan Sheridan, NP


Stop Diagnosing Everything: Why We Need a Holistic Psychiatry Revolution (in St. Louis, MO and beyond)
We’ve built a mental health culture where every hard experience becomes a label—and every label leads to a prescription. That’s not...
Ryan Sheridan, NP


Deprescribing: Reclaiming Health, Reclaiming Power
In the world of psychiatry today, we hear a lot about starting medications. Less often do we hear about stopping them. We live in a...
Ryan Sheridan, NP


SSRIs & Metabolic Health: The Hidden Impact on Your Metabolism, Insulin Resistance, and Gut Health (And How to Fix It)
SSRIs have saved lives, I'm sure. Let’s get that straight. But they’re not a free pass to long-term wellness. What most prescribers...
Ryan Sheridan, NP


SSRIs, Dementia, and the Case for Metabolic Psychiatry: Why We Need to Rethink Mental Health Treatment
A massive new cohort study just confirmed what many of us have suspected for years: SSRIs accelerate cognitive decline in dementia...
Ryan Sheridan, NP


Do SSRIs Really Work? The Truth About Their Effectiveness, Risks, and Metabolic Side Effects
Selective serotonin reuptake inhibitors (SSRIs) are some of the most widely prescribed medications for depression and anxiety, but how...
Ryan Sheridan, NP


ADHD: A Crisis of Diagnosis, Outcomes, and the Need for Real Solutions
Attention-Deficit/Hyperactivity Disorder (ADHD) has become one of the most talked-about mental health conditions in the last few decades,...
Ryan Sheridan, NP


Methylation: The Link Between Methylation and Mental Health
As an integrative psychiatric nurse practitioner in Washington, DC , I’m always seeking the most effective ways to support my patients in...
Ryan Sheridan, NP


Magnesium for Depression, Anxiety, and Sleep: A Guide for Magnesium Supplementation
In this blog post we will discuss all things magnesium! Magnesium is frequently praised for its calming effects on stress and mood....
Ryan Sheridan, NP


ADHD Across Ages: Integrative Approaches in Washington, D.C.
As an integrative psychiatric nurse practitioner based in Washington, D.C., I am uniquely positioned to observe the challenges and...
Ryan Sheridan, NP


The Integrative Path to Mental Wellness in Washington, DC: Beyond Medication
Integrative psychiatry redefines our approach to mental wellness. It's common to leave a provider’s office with a prescription as the...
Ryan Sheridan, NP


Rethinking Polypharmacy in Mental Health: A Holistic Approach in Washington, DC.
As an integrative psychiatric nurse practitioner in Washington, D.C., my practice is anchored in the belief that holistic treatments,...
Ryan Sheridan, NP


Why Your Psychiatric Medication May Be Holding You Back from Success
Amidst the hustle and the never-ending quest for personal and professional success, there's a nuanced conversation we need to have. It's...
Ryan Sheridan, NP


What Supplements Are Good for ADHD and Focus? A Nutritional Psychiatry Deep Dive
There are a bunch of supplements that can be used to help improve symptoms of ADHD and focus in general.
Ryan Sheridan, NP
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